Linezolid impurity 104 CAS 1644566-17-5
| CAS No. | 1644566-17-5 |
| Molecular Formula | C18H12F2N2O4 |
| Molecular Weight | 358.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 358.30 g/mol gives Linezolid impurity 104 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Linezolid impurity 104 (CAS 1644566-17-5, C18H12F2N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Linezolid impurity 104 (C18H12F2N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Linezolid impurity 104 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12F2N2O4 |
| Molecular Weight | 358.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Linezolid Standards
- Linezolid Impurity 66 (CAS CATO-C4X-107366)
- Linezolid Impurity 11 (CAS 1394245-06-7)
- Linezolid Impurity 122 (CAS CATO-C4X-1073122)
- Linezolid USP Related Compound B (CAS 216868-57-4)
- Linezolid Impurity 100 (CAS CATO-C4X-1073100)
- Linezolid lmpurity 101 (CAS CATO-C4X-1073101)
- Linezolid Impurity 1 (CAS 189038-36-6)
- Linezolid Impurity 11 (CAS 1215006-08-8)
Recommended Standards
- Regorafenib Impurity 81 (CAS CATO-C4X-104781)
- Ramipril EP Impurity M (CAS 2743-38-6)
- 6-O-α-D-Galactopyranosyl-D-gluconic acid (CAS 70803-54-2)
- Phloroglucinol Impurity 76 (CAS CATO-C4X-221776)
- Mianserin Impurity 111 (CAS CATO-C4X-1369111)
- Difelikefalin Impurity 60 (CAS 1821319-29-2)
- Potassium Clavulanate EP Impurity K (CAS 107-45-9)
- 3-(N-Boc-N-Methylamino)-2-chloropyridine-5-boronic acid (CAS 2377608-21-2)
- Methyl 5-(aminomethyl)pyridine-2-carboxylate dihydrochloride (CAS 1375471-89-8)
- N-(2-methanesulfonylethyl)cyclopropanamine (CAS 947723-53-7)
- Cefaclor EP Impurity G-Isomer 1 (CAS 67308-21-8)
- 5-(9H-Carbazol-9-yl)pentane-1-thiol (CAS 397250-48-5)
- 1-cyclopropyl-6-methyl-1,4-diazepane (CAS 1250809-59-6)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com