Ethyl 5-amino-1-(3-nitrophenyl)pyrazole-4-carboxylate CAS 16459-34-0
| CAS No. | 16459-34-0 |
| Molecular Formula | C12H12N4O4 |
| Molecular Weight | 276.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-amino-1-(3-nitrophenyl)pyrazole-4-carboxylate.
Ethyl 5-amino-1-(3-nitrophenyl)pyrazole-4-carboxylate (CAS 16459-34-0), molecular formula C12H12N4O4 and molecular weight 276.25 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 5-amino-1-(3-nitrophenyl)pyrazole-4-carboxylate (C12H12N4O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 5-amino-1-(3-nitrophenyl)pyrazole-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12N4O4 |
| Molecular Weight | 276.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- Ethyl 5-amino-1-(2-nitrophenyl)-1H-pyrazole-3-carboxylate (CAS 1264045-48-8)
- Ethyl 5-amino-1-(3-nitrophenyl)-1H-pyrazole-3-carboxylate (CAS 1264049-67-3)
- Methyl 5-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-1,2,3-triazole-4-carboxylate (CAS 1411766-56-7)
- 4-Amino-N,N-dimethyl-3-((1,1,1-trifluoropropan-2-yl)oxy)benzamide (CAS 1509183-62-3)
- Ethyl 5-amino-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylate (CAS 16459-33-9)
- Ethyl 5-amino-1-(4-nitrophenyl)-1h-pyrazole-4-carboxylate (CAS 16459-35-1)
- 4-Amino-2-((benzyloxy)methyl)-5-nitropyridazin-3(2H)-one (CAS 92574-77-1)
- Ethyl 5-amino-1-(4-nitrophenyl)-1H-pyrazole-3-carboxylate (CAS 866838-08-6)
Recommended Standards
- Ethyl 5-methyl-1-(4-nitrophenyl)-1H-1,2,4-triazole-3-carboxylate (CAS 15966-46-8)
- Uracil Impurity 4 (CAS 17014-74-3)
- Ethyl 5-methyl-1-(4-nitrophenyl)-1h-1,2,3-triazole-4-carboxylate (CAS 15922-66-4)
- (2-Methoxypyrimidin-5-yl)methyl 2-methoxypyrimidine-5-carboxylate (CAS 1707587-03-8)
- (4-(1H-1,2,3-triazol-1-yl)phenyl)methanol (CAS 887590-19-4)
- 3-Chloro-3-(3-methoxyphenyl)propiophenone (CAS 898774-68-0)
- 5-Chloro-4-(dichloromethyl)-3-(4-nitrophenyl)isoxazole (CAS 116470-17-8)
- (5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 2514801-98-8)
- (3S)-1-methylpyrrolidine-3-carboxylic acid (CAS 952484-58-1)
- 6-(Trifluoromethyl)isoindolin-5-amine (CAS 905273-62-3)
- Tert-butyl 8-oxa-3,10-diazabicyclo[4.3.1]Decane-10-carboxylate (CAS 1331848-02-2)
- Ethyl 2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-1H-tetrazol-1-yl)acetate (CAS 1030613-24-1)
- Monophosphoryl lipid A (CAS 1246298-63-4)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
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