1-(2,4-Dichlorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid CAS 164662-42-4
| CAS No. | 164662-42-4 |
| Molecular Formula | C20H16Cl2FN3O3 |
| Molecular Weight | 436.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-(2,4-Dichlorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 436.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(2,4-Dichlorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 164662-42-4), molecular formula C20H16Cl2FN3O3 and molecular weight 436.26 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16Cl2FN3O3 |
| Molecular Weight | 436.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorophenyl Standards
- 5-(3,4-Dichlorophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 477333-00-9)
- Ethyl 1-(4-(3,4-dichlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956961-73-2)
- Ethyl 1-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 955964-59-7)
- 2-(2,4-Dichlorophenyl)-2-oxoethyl 2-phenylquinoline-4-carboxylate (CAS 355434-00-3)
- 3-(2,4-Dichlorophenyl)-N-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 477853-44-4)
- 3-(3,4-Dichlorophenyl)-N-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 338977-97-2)
- 4-(2,5-Dichlorophenyl)azo-3-hydroxy-N-phenylnaphthalene-2-carboxamide (CAS 6041-94-7)
- 4-[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-N-(3-methoxypropyl)-1H-pyrrole-2-carboxamide (CAS 478064-48-1)
Recommended Standards
- 4,4'-[(Perfluorocyclobutane-1,2-diyl)bis(oxy)]dibenzoic acid (CAS 134151-61-4)
- Pomalidomide-CO-C4-Br (CAS 2162120-76-3)
- Ethyl 4-(2-(5-bromo-4-formyl-2-methoxyphenoxy)acetamido)benzoate (CAS 692266-78-7)
- VX 745 (CAS 209410-46-8)
- ITIC-4Cl / IT-4Cl (CAS 2253663-81-7)
- (2-(N-Butylacetamido)oxazol-5-yl)methyl acetate (CAS 57068-25-4)
- 4-(4-(Tert-butyl)benzoyl)-N-(2-(pyridin-2-yl)ethyl)-1H-pyrrole-2-carboxamide (CAS 439111-46-3)
- 6-Chloro-7-fluoroquinazolin-2-amine (CAS 2763595-61-3)
- 6-(4-Methoxyphenyl)-2-(2-methylbenzyl)pyridazin-3(2H)-one (CAS 899989-96-9)
- 3-benzyl-2-thioxoimidazolidin-4-one (CAS 39123-65-4)
- 2-Methyl-1H-indole-5-carboxylic Acid (CAS 496946-80-6)
- Methyl 3-(benzyloxy)-2,4-difluorobenzoate (CAS 2635937-53-8)
- N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-((1-(o-tolyl)-1H-tetrazol-5-yl)thio)acetamide (CAS 838894-38-5)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com