Pomalidomide-CO-C4-Br CAS 2162120-76-3
| CAS No. | 2162120-76-3 |
| Molecular Formula | C18H18BrN3O5 |
| Molecular Weight | 436.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pomalidomide-CO-C4-Br.
Pomalidomide-CO-C4-Br (CAS 2162120-76-3), molecular formula C18H18BrN3O5 and molecular weight 436.26 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Pomalidomide-CO-C4-Br is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 436.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18BrN3O5 |
| Molecular Weight | 436.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Pomalidomide Standards
- Pomalidomide-C6-Br (CAS 2355289-53-9)
- Pomalidomide-acetamido-O-PEG1-C2-Cl (CAS 2162120-92-3)
- Pomalidomide-5'-PEG2-C2-acid (CAS 2412056-45-0)
- Pomalidomide-PEG2-C2-azide (CAS 2271036-45-2)
- Pomalidomide-5'-PEG3-propargyl (CAS 2230825-39-3)
- Pomalidomide-PEG3-propargyl (CAS 2138439-57-1)
- Pomalidomide-CO-PEG2-propargyl (CAS 2243000-25-9)
- Pomalidomide Impurity 39 (CAS 2093416-31-8)
Recommended Standards
- 1-(2,4-Dichlorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 164662-42-4)
- VX 745 (CAS 209410-46-8)
- 4,4'-[(Perfluorocyclobutane-1,2-diyl)bis(oxy)]dibenzoic acid (CAS 134151-61-4)
- 6-Bromo-1-(tert-Butyldimethylsilyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1256358-99-2)
- 1-(Methoxycarbonyl)piperidine-3-carboxylic acid (CAS 1019363-10-0)
- 7411-16-7 3-Ethyl-1,2,4(1H)-triazole DTXSID40225058 (CAS 7411-16-7)
- Ethyl 2-(4-chloro-3-fluorophenyl)-2-hydroxyacetate (CAS 1247619-04-0)
- 2,3-Dihydroimidazo[1,2-c]pyrimidin-5(1H)-one (CAS 63934-46-3)
- 2-((Benzo[b]selenophen-2-ylmethyl)thio)ethyl benzoate (CAS 61776-21-4)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((((2-chlorobenzyl)oxy)carbonyl)amino)pentanoic acid (CAS 198561-86-3)
- methyl 3-ethoxy-4-formylbenzoate (CAS 1357352-32-9)
- 2-Cyclopropyl-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 136204-42-7)
- 2-(3-phenyl-1,2,4-oxadiazol-5-yl)propan-1-amine (CAS 1423028-18-5)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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