2-Chlorophenyl sulfurochloridate CAS 16475-31-3
| CAS No. | 16475-31-3 |
| Molecular Formula | C6H4Cl2O3S |
| Molecular Weight | 227.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chlorophenyl sulfurochloridate (CAS 16475-31-3), molecular formula C6H4Cl2O3S and molecular weight 227.07 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2-Chlorophenyl sulfurochloridate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4Cl2O3S |
| Molecular Weight | 227.07 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 3-Chlorophenyl sulfurochloridate (CAS 67628-46-0)
- 4-Chlorophenyl chloranesulfonate (CAS 32117-86-5)
- (4-Chlorophenyl)triethylsilane (CAS 18037-03-1)
- N-(4-Chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine (CAS 103039-04-9)
- N-(2-Chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine (CAS 27779-16-4)
- n-(4-Chlorophenyl)-4-methyl-4,5-dihydro-1,3-thiazol-2-amine (CAS 379728-04-8)
- N-(4-Chlorophenyl)-5-methyl-4,5-dihydro-1,3-thiazol-2-amine (CAS 75220-48-3)
- n-[(4-chlorophenyl)methyl]-4,5-dihydro-1,3-thiazol-2-amine (CAS 72239-29-3)
Recommended Standards
- 2-Amino-5-chloropyridine-3-sulfonyl chloride (CAS 163137-45-9)
- 4,5-Dichloro-2-(methylsulfonyl)pyrimidine (CAS 1803805-58-4)
- {1-[(tert-Butoxy)carbonyl]-1,2,5,6-tetrahydropyridin-3-yl}boronic acid (CAS 1451153-83-5)
- 2,5-Dichloro-4-(methylsulfonyl)pyrimidine (CAS 1806288-80-1)
- (1-Cyano-2-propanyl)(dodecyl)ethylsulfonium tetrafluoroborate (CAS 72140-65-9)
- 2,4-Diethylaniline (CAS 14719-47-2)
- 1,6-O,O-diacetylbritannilactone (CAS 151513-70-1)
- (R)-2-(3,4-dimethoxyphenyl)-2-(methylamino)ethan-1-ol (CAS 1336325-28-0)
- 3-(5-(Allylthio)-1,3,4-oxadiazol-2-yl)-1-(2,4-dichlorobenzyl)pyridin-2(1H)-one (CAS 477853-17-1)
- 5-[(3,4-Dichlorophenyl)sulfanyl]-4-phenyl-1,2,3-thiadiazole (CAS 338398-34-8)
- Rimegepant Impurity 21 (CAS CATO-C4X-248721)
- (2-Chloro-6-fluorobenzyl)(ethyl)sulfane (CAS 1443340-29-1)
- 5-Bromo-N-cyclobutyl-2-fluorobenzamide (CAS 1249811-13-9)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
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