4-chloro-6-(trifluoromethyl)quinazoline CAS 16499-64-2
| CAS No. | 16499-64-2 |
| Molecular Formula | C9H14ClF3N2 |
| Molecular Weight | 242.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-chloro-6-(trifluoromethyl)quinazoline.
4-chloro-6-(trifluoromethyl)quinazoline (CAS 16499-64-2) is a high-purity analytical reference standard with the molecular formula C9H14ClF3N2 and a molecular weight of 242.67 g/mol.
Owing to a nitrile group, fluorine/chlorine substitution, 4-chloro-6-(trifluoromethyl)quinazoline is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-chloro-6-(trifluoromethyl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H14ClF3N2 |
| Molecular Weight | 242.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- 1-(4-Chloro-2-fluorophenyl)cyclopentane-1-carboxylic acid (CAS 1260775-49-2)
- 1-(3-Chloro-2-fluorophenyl)cyclopentanecarboxylic Acid (CAS 1260826-07-0)
- Benzyl 2-(2-chloro-2-fluorocyclopropyl)acetate (CAS 132656-21-4)
- 4-chloro-2-(difluoromethyl)-6-fluoroquinazoline (CAS 1342755-17-2)
- 5-chloro-3-(trifluoromethyl)-1,6-naphthyridine (CAS 1352935-05-7)
- 2-chloro-6-(trifluoromethyl)quinazoline (CAS 1388025-17-9)
- 8-chloro-3-(trifluoromethyl)-1,7-naphthyridine (CAS 1393570-24-5)
- 3-(2-Chloro-6-fluorobenzyl)pentane-2,4-dione (CAS 175136-74-0)
Recommended Standards
- 3-Trifluoromethylsulfanyl-propane-1-sulfonyl chloride (CAS 1422766-26-4)
- 1-(4-Chloro-3-fluorophenyl)cyclopentanecarboxylic Acid (CAS 1782204-52-7)
- 1-(3-Chloro-4-fluorophenyl)cyclopentanecarboxylic Acid (CAS 1891500-97-2)
- 1-(2-Chloro-4-fluorophenyl)cyclopentanecarboxylic Acid (CAS 214263-01-1)
- N2-((2-Cyclobutylthiazol-4-yl)methyl)pyridine-2,3-diamine (CAS 1713476-97-1)
- 2-((5-((tert-Butoxycarbonyl)amino)pentyl)amino)acetic acid (CAS 630095-93-1)
- 2-(2-((1-(3-Methylthiophen-2-yl)ethyl)amino)ethoxy)ethan-1-ol (CAS 1342002-56-5)
- 1-[4-(4-chloro-but-2-ynyloxy)-phenyl]-ethanone (CAS 1284229-49-7)
- 6-Bromo-5-methylbenzo[d]isoxazol-3-amine (CAS 2385483-19-0)
- 3-Methyl-N-(1-(pyridin-3-yl)ethyl)butan-2-amine (CAS 1042582-75-1)
- 1-Amino-3-methoxypropan-2-ol hydrochloride (CAS 60812-33-1)
- 5-Bromoimidazo[1,2-a]pyridinehydrobromide (CAS 603301-13-9)
- Pentoxyverine Impurity 23 (CAS CATO-C4X-227023)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com