Difluoro(Phenylsulfanyl)Acetyl Chloride CAS 16503-77-8
| CAS No. | 16503-77-8 |
| Molecular Formula | C8H5ClF2OS |
| Molecular Weight | 222.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Difluoro(Phenylsulfanyl)Acetyl Chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Difluoro(Phenylsulfanyl)Acetyl Chloride (CAS 16503-77-8), molecular formula C8H5ClF2OS and molecular weight 222.64 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Difluoro(Phenylsulfanyl)Acetyl Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2OS |
| Molecular Weight | 222.64 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- 6,8-Difluoro-2-propylquinolin-4-amine (CAS 1189105-83-6)
- 7,8-Difluoro-2-propylquinolin-4-amine (CAS 1189106-87-3)
- 4,4-Difluoro-1-(2-methoxyethyl)cyclohexane-1-carboxylic acid (CAS 1389315-15-4)
- ((1S)-2,2-Difluoro-1-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)cyclopropyl)methanol (CAS 2875129-59-0)
- (R)-6,9-difluoro-3-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 2408686-95-1)
- (S)-6,9-difluoro-3-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 2408686-87-1)
- 2,2-Difluoro-2-(1-hydroxy-4,4-dimethylcyclohexyl)acetic acid (CAS 681240-24-4)
- 2,2-Difluoro-N-(3-morpholinopropyl)acetamide (CAS 570421-59-9)
Recommended Standards
- 3-(2,2-Difluoroethoxy)propane-1-sulfonyl chloride (CAS 1555211-53-4)
- 2'-Chloro-6'-fluoro-[1,1'-biphenyl]-2-ol (CAS 1879712-94-3)
- 4-(3-Chloro-5-fluorophenyl)phenol (CAS 1262001-95-5)
- 1-Chloro-4-(3-fluorophenoxy)benzene (CAS 1881289-06-0)
- 4-Methylquinoline-7-carboxylic acid (CAS 52287-41-9)
- 1-Amino-2,4-dibromonaphthalene (CAS 20191-76-8)
- 2,6-Dimethyldithieno[3,2-b:2',3'-d]thiophene (CAS 533930-12-0)
- N-(4-amino-2,6-dichlorophenyl)thiophene-3-carboxamide (CAS 926204-45-7)
- 4-Methyl-6-phenyl-2-thiocyanatopyrimidine (CAS 55055-29-3)
- 3-((3-Bromophenyl)carbamoyl)-2,2,3-trimethylcyclopentane-1-carboxylic acid (CAS 497060-73-8)
- Rhodiolinin (CAS 86831-53-0)
- (4-Fluoro-3-phenoxyphenyl)methanol (CAS 68359-53-5)
- 3-(Phenylsulfonyl)pyrazine-2-carbonitrile (CAS 74002-68-9)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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