7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol CAS 16503-92-7

Purity 97%+In StockPharmaceutical Standards
CAS No.16503-92-7
Molecular FormulaC11H15NO3
Molecular Weight209.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol CAS 16503-92-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol.

CATO supplies 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol (CAS 16503-92-7), a certified reference material (molecular formula C11H15NO3, MW 209.24 g/mol) for analytical method development and quality control.

The molecular framework of 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol (C11H15NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H15NO3
Molecular Weight209.24 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms1

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