4-(((tert-Butoxycarbonyl)amino)methyl)-3-chlorobenzoic acid CAS 165528-69-8
| CAS No. | 165528-69-8 |
| Molecular Formula | C13H16ClNO4 |
| Molecular Weight | 285.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-(((tert-Butoxycarbonyl)amino)methyl)-3-chlorobenzoic acid (CAS 165528-69-8), a certified reference material (molecular formula C13H16ClNO4, MW 285.72 g/mol) for analytical method development and quality control.
The molecular framework of 4-(((tert-Butoxycarbonyl)amino)methyl)-3-chlorobenzoic acid (C13H16ClNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16ClNO4 |
| Molecular Weight | 285.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 3-(((tert-Butoxycarbonyl)amino)methyl)-4-chlorobenzoic acid (CAS 153346-57-7)
- 5-(((tert-Butoxycarbonyl)amino)methyl)-2-chlorobenzoic acid (CAS 165950-04-9)
- [(tert-butoxycarbonyl)amino](3-chlorophenyl)acetic acid (CAS 669713-92-2)
- 2-((tert-Butoxycarbonyl)(methyl)amino)-4-chlorobenzoicacid (CAS 886362-06-7)
- 2-((tert-Butoxycarbonyl)(methyl)amino)-5-chlorobenzoicacid (CAS 886362-04-5)
- 2-((tert-Butoxycarbonyl)amino)-2-(2-chlorophenyl)acetic acid (CAS 313490-25-4)
- 2-((tert-Butoxycarbonyl)amino)-4-chloro-3-methylbenzoic acid (CAS 2248287-49-0)
- 2-(tert-Butoxycarbonyl(2-chlorophenyl)amino)acetic acid (CAS 225918-60-5)
Recommended Standards
- tert-Butyl (4-chloro-2-formyl-5-methoxyphenyl)carbamate (CAS 1632286-03-3)
- Methyl 4-acetamido-5-chloro-2-isopropoxybenzoate (CAS 172093-28-6)
- Methyl 2-((tert-butoxycarbonyl)amino)-5-chlorobenzoate (CAS 1495813-19-8)
- (6-Amino-3-methylbenzofuran-2-yl)(4-chlorophenyl)methanone (CAS 174344-22-0)
- tert-Butyl n-(diethoxyphosphorylmethyl)carbamate (CAS 350027-05-3)
- 2-Benzyloxy-5-formyl-3-methoxybenzeneboronic acid (CAS 2096333-82-1)
- (3S,5S)-5-methylpyrrolidin-3-amine (CAS 684644-42-6)
- 175137-39-0 3-amino-5-(4-fluorophenyl)-2-thiophenecarbonitrile 3-azanyl-5-(4-fluorophenyl)thiophene-2-carbonitrile A811793 (CAS 175137-39-0)
- 5-(2-hydroxyethyl)-1,2-dihydropyrimidin-2-one hydrochloride (CAS 1803571-24-5)
- tert-Butyl (2S)-2-(aminomethyl)-2-propylpyrrolidine-1-carboxylate (CAS 1630815-56-3)
- N2-Cyclobutyl-N2-methylthiazole-2,4-diamine (CAS 1365940-22-2)
- 1-[4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid (CAS 870980-07-7)
- 4-Chloro-5-methylindoline-2,3-dione (CAS 53003-18-2)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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