1-[4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid CAS 870980-07-7
| CAS No. | 870980-07-7 |
| Molecular Formula | C18H18F3N3O3 |
| Molecular Weight | 381.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid.
CATO supplies 1-[4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid (CAS 870980-07-7), a certified reference material (molecular formula C18H18F3N3O3, MW 381.35 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-[4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 381.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18F3N3O3 |
| Molecular Weight | 381.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related methoxyphenyl Standards
- 2-((4-Methoxyphenyl)sulfonyl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 339014-02-7)
- 6-(4-Methoxyphenyl)-2-((3,4,4-trifluorobut-3-en-1-yl)thio)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 672951-82-5)
- Ethyl 4-{[(4-methoxyphenyl)methyl]amino}-6-nitroquinoline-3-carboxylate (CAS 478248-28-1)
- Ethyl 5-[(4-methoxyphenyl)sulfanyl]-3-(4-methylphenyl)-1,2,4-triazine-6-carboxylate (CAS 866049-03-8)
- N-(4-methoxyphenyl)-2-(2-(naphthalen-1-yloxy)acetyl)hydrazine-1-carbothioamide (CAS 903833-98-7)
- 1-((4-Methoxyphenyl)sulfonyl)-N-(thiazol-2-yl)piperidine-4-carboxamide (CAS 904011-46-7)
- 3-(2-Methoxyphenyl)-2,5-dimethyl-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 902041-09-2)
- N-(3-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)propyl)cyclopropanecarboxamide (CAS 1020981-95-6)
Recommended Standards
- 1-(Isoxazolidin-2-yl)-2-(4-(4-(trifluoromethyl)phenoxy)phenoxy)propan-1-one (CAS 88081-63-4)
- (Z)-3-(3-(3-(trifluoromethyl)phenoxy)benzylidene)indolin-2-one (CAS 860784-43-6)
- 4-[(4-Fluorobenzyl)oxy]benzyl 3-nitrobenzenecarboxylate (CAS 331461-75-7)
- (2Z)-2-[(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene]-2,3-dihydro-1H-inden-1-one (CAS 268563-95-7)
- Ethyl 7-Chloroimidazo[1,2-a]pyridine-3-carboxylate (CAS 1296201-68-7)
- 3-methyl-1-phenyl-5-pyrrolidin-1-yl-1H-pyrazole-4-carbaldehyde oxime (CAS 882226-97-3)
- N-Cyclohexyl-2-((7-oxo-5-propyl-7,8-dihydro-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio)acetamide (CAS 891123-32-3)
- 1-(2-methylpropyl)pyrrolidine-2-carbaldehyde (CAS 1706439-05-5)
- Ethyl 3-Methyl-3-Phenylglycidate (CAS 77-83-8)
- Adenosine-5'-triphosphate tetrasodium (CAS 606-67-7)
- PEG4-phosphonic acid (CAS 750541-89-0)
- Vercirnon (CAS 698394-73-9)
- tert-Butyl 2,5-diiodopyridin-3-yl carbonate (CAS 1138444-30-0)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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