Ethyl 2,2-Difluoro-3-methyl-butyrate CAS 165544-22-9
| CAS No. | 165544-22-9 |
| Molecular Formula | C7H12F2O2 |
| Molecular Weight | 166.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 2,2-Difluoro-3-methyl-butyrate (CAS 165544-22-9), a certified reference material (molecular formula C7H12F2O2, MW 166.17 g/mol) for analytical method development and quality control.
Structurally, Ethyl 2,2-Difluoro-3-methyl-butyrate (C7H12F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 166.17 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Ethyl 2,2-Difluoro-3-methyl-butyrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12F2O2 |
| Molecular Weight | 166.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 4,4-difluoro-1-(hydroxymethyl)cyclohexanol (CAS 1256545-48-8)
- 3,3-Difluoro-2,2-dimethylpentanoic acid (CAS 2090954-33-7)
- 3,3-Difluoro-4-hydroxy-2-heptanone (CAS 93233-42-2)
- 4,4-Difluoro-3,3-dimethylpentanoic acid (CAS 2024430-38-2)
- 5,5-Difluoro-3,3-dimethylpentanoic acid (CAS 2026374-42-3)
- 2,3-difluoro-5-nitro-pyridine (CAS 954219-68-2)
- 2,4-difluoro-5-nitro-pyridine (CAS 60186-15-4)
- 2,6-difluoro-3-nitro-pyridine (CAS 58602-02-1)
Recommended Standards
- Acetovanillone Sodium Salt (CAS 16522-48-8)
- 2-Hydroxy-5-isopropylcyclohexa-2,5-diene-1,4-dione (CAS 167315-66-4)
- (3-Methylphenoxy)acetic Acid (CAS 1643-15-8)
- Phenyl 2-Methoxyacetate (CAS 16839-92-2)
- 5-(Benzyloxy)-8-(oxiran-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1822826-25-4)
- (4-Fluoro-6-(piperidin-1-yl)pyridin-3-yl)boronic acid (CAS 2225174-76-3)
- (2-Fluoro-4-methyl-5-nitrophenyl)methanol (CAS 1806480-23-8)
- 1-Hydroxy-4-phenyl-1H-1,2,3-triazole-5-carboxylic acid (CAS 887405-55-2)
- DABIGATRAN ETEXILATE (CAS 1610666-09-5)
- 2-(4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)acetonitrile (CAS 905966-41-8)
- 2-Methylbutane-1,4-diamine dihydrochloride (CAS 111469-11-5)
- 4-(4-Fluoro-3-methylphenyl)butan-2-one (CAS 1017209-93-6)
- 5-(tert-Butyl)-2-methoxy-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide (CAS 714209-45-7)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com