2-(Azetidin-3-yl)pyridine 2,2,2-trifluoroacetic acid CAS 1659301-72-0
| CAS No. | 1659301-72-0 |
| Molecular Formula | C8H10N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Azetidin-3-yl)pyridine 2,2,2-trifluoroacetic acid (CAS 1659301-72-0) is a high-purity analytical reference standard with the molecular formula C8H10N2C2HF3O2 and a molecular weight of 248.20 g/mol.
The molecular framework of 2-(Azetidin-3-yl)pyridine 2,2,2-trifluoroacetic acid (C8H10N2C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Azetidin-3-yl)pyridine 2,2,2-trifluoroacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N2 C2HF3O2 |
| Molecular Weight | 248.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Azetidin Standards
- 4-(Azetidin-1-yl)cyclohexan-1-amine dihydrochloride (CAS 1001347-27-8)
- 4-(Azetidin-1-ylmethyl)-1H-indole (CAS 1001395-40-9)
- 2-(Azetidin-1-yl)acetic acid (CAS 1008304-81-1)
- Azetidin-3-yl methylcarbamate hydrochloride (CAS 1009368-29-9)
- 5-(Azetidin-3-yl)-2-methyl-tetrazole (CAS 1009409-58-8)
- 2-((Azetidin-3-yloxy)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1009409-61-3)
- Azetidin-3-yl methylcarbamate (CAS 1009409-62-4)
- 1-(Azetidin-3-ylmethyl)piperidine (CAS 1012784-24-5)
Recommended Standards
- (2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-methylprop-2-enethioamide (CAS 338422-38-1)
- 5-Chloro-1,3-difluoro-2-methylbenzene (CAS 1208076-23-6)
- Methyl 2-{[amino(imino)methyl]thio}-3-oxobutanoate hydrochloride (CAS 1212061-58-9)
- 6-methoxy-4-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 929974-06-1)
- 1-(7-Methyl-2-(prop-2-yn-1-ylthio)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one (CAS 886152-14-3)
- Carbocisteine Impurity 59 (CAS CATO-C4X-201059)
- 2-Chloro-N-cyclopropyl-N-((3-methoxypyrazin-2-yl)methyl)acetamide (CAS 1353984-73-2)
- Carteolol EP Impurity F (CAS 2748462-60-2)
- 6-Bromo-2-phenylimidazo[1,2-a]pyridin-7-amine (CAS 1278407-63-8)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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