(2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-methylprop-2-enethioamide CAS 338422-38-1
| CAS No. | 338422-38-1 |
| Molecular Formula | C15H16ClF3N6S |
| Molecular Weight | 404.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, (2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-methylprop-2-enethioamide (C15H16ClF3N6S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 404.84 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-methylprop-2-enethioamide (CAS 338422-38-1), molecular formula C15H16ClF3N6S and molecular weight 404.84 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-methylprop-2-enethioamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H16ClF3N6S |
| Molecular Weight | 404.84 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
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Recommended Standards
- N-(2-Chloro-4-nitrophenyl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332357-70-7)
- 6-(2-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-48-7)
- 4-((3-Chloro-4-fluorophenyl)amino)-6-((pyridin-3-ylmethyl)amino)-1,7-naphthyridine-3-carbonitrile (CAS 871307-18-5)
- 6-(4-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-45-4)
- Methyl 2-(2-Pyrrolidinyl)benzoate Hydrochloride (CAS 1203681-57-5)
- 4-hydroxy-6-methylbenzene-1,3-disulfonic acid (CAS 15509-33-8)
- Methyl 2-amino-3-oxobutanoate hydrochloride (CAS 41172-77-4)
- (9H-Fluoren-9-yl)methyl (R)-(1-aminopropan-2-yl)carbamate hydrochloride (CAS 2411590-71-9)
- 6-(Iodomethyl)-5-oxaspiro[3.4]octane (CAS 1849359-21-2)
- Rosuvastatin Impurity 184 (CAS CATO-C4X-1169184)
- 8-Methoxy-4-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid (CAS 16035-97-5)
- 6-fluoro-3H-benzimidazole-4-carboxylic acid (CAS 1193387-31-3)
- 4,6-Dichloro-2-(pyrrolidin-2-yl)pyrimidine hydrochloride (CAS 2306270-83-5)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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