4-Chloro-3-hydroxybenzoic Acid Methyl Ester CAS 166272-81-7
| CAS No. | 166272-81-7 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-3-hydroxybenzoic Acid Methyl Ester is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Chloro-3-hydroxybenzoic Acid Methyl Ester (CAS 166272-81-7) is a high-purity analytical reference standard with the molecular formula C8H7ClO3 and a molecular weight of 186.59 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-Chloro-3-hydroxybenzoic Acid Methyl Ester is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-3-hydroxybenzoic Acid Methyl Ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 4-Chloro-2-(hydroxymethyl)benzoic acid (CAS 100448-59-7)
- Methyl 2-Chloro-4-hydroxybenzoate (CAS 104253-44-3)
- 3-Chloro-2,4-dihydroxy-6-methylbenzaldehyde (CAS 106325-72-8)
- 2-Chloro-4-(hydroxymethyl)benzoic acid (CAS 1071989-48-4)
- Methyl 2-chloro-3-hydroxybenzoate (CAS 1125632-11-2)
- 2-Chloro-6-hydroxy-4-methoxybenzaldehyde (CAS 116475-68-4)
- 2-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-13-6)
- 4-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-15-8)
Recommended Standards
- 3-Chloro-4-(hydroxymethyl)-benzoic Acid (CAS 1594779-14-2)
- Methyl 2-chloro-6-hydroxybenzoate (CAS 176750-70-2)
- 5-Chloro-4-hydroxy-2-methylbenzoic acid (CAS 1555855-22-5)
- 1-(3-Chlorophenyl)-2,2-dihydroxyethan-1-one (CAS 177288-16-3)
- 5-Fluoro-2,3-dihydro-1H-inden-2-amine (CAS 2340-06-9)
- 2-(Bromomethyl)-6-(difluoromethyl)-3-methoxypyridine-4-acetonitrile (CAS 1361708-66-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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