5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride CAS 166964-33-6

Purity 97%+In StockPharmaceutical Standards
CAS No.166964-33-6
Molecular FormulaC9H6Cl2O2S2
Molecular Weight281.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride CAS 166964-33-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 281.18 g/mol gives 5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride (CAS 166964-33-6) is a high-purity analytical reference standard with the molecular formula C9H6Cl2O2S2 and a molecular weight of 281.18 g/mol.

5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride (C9H6Cl2O2S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H6Cl2O2S2
Molecular Weight281.18 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Halogen ContentCl-containing
Sulfur Atoms2

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