6-Chloro-3-methyl-1-benzothiophene-2-sulfonyl chloride CAS 752135-37-8
| CAS No. | 752135-37-8 |
| Molecular Formula | C9H6Cl2O2S2 |
| Molecular Weight | 281.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 281.18 g/mol gives 6-Chloro-3-methyl-1-benzothiophene-2-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-Chloro-3-methyl-1-benzothiophene-2-sulfonyl chloride (CAS 752135-37-8), a certified reference material (molecular formula C9H6Cl2O2S2, MW 281.18 g/mol) for analytical method development and quality control.
The molecular framework of 6-Chloro-3-methyl-1-benzothiophene-2-sulfonyl chloride (C9H6Cl2O2S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Chloro-3-methyl-1-benzothiophene-2-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6Cl2O2S2 |
| Molecular Weight | 281.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Chloro Standards
- 5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride (CAS 166964-33-6)
- 4-Chloro-3-methyl-1-benzothiophene-2-sulfonyl chloride (CAS 752135-45-8)
- 5-Chloro-2-methyl-1-benzothiophene-3-sulfonyl chloride (CAS 220432-04-2)
- 7-Chloro-2-methylbenzo[b]thiophene-3-sulfonyl chloride (CAS 338797-01-6)
- 4-Chloro-5-(2-chlorophenyl)thieno[2,3-d]pyrimidine (CAS 1133128-92-3)
- 5-chloro-2-(cyclopropylmethoxy)benzene-1-sulfonyl chloride (CAS 1248472-51-6)
- 4-Chloro-2-(2-chlorophenyl)thieno[3,2-d]pyrimidine (CAS 383146-17-6)
- 4-Chloro-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine (CAS 331761-46-7)
Recommended Standards
- Cloperastine Impurity 5 (CAS 75842-85-2)
- 4,4,5,5-Tetramethyl-2-(3-(S-methylsulfonimidoyl)phenyl)-1,3,2-dioxaborolane (CAS 2845282-12-2)
- Meclozine Impurity 2 (CAS 5321-46-0)
- 2-(Tetrahydrofuran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 2222997-47-7)
- (2,5-Dibromo-3,6-difluorophenyl)methanol (CAS 1804882-96-9)
- Ethyl 3-(3-fluorophenyl)-5-methylisoxazole-4-carboxylate (CAS 917388-62-6)
- 2-((1-(Pyrrolidin-1-ylmethyl)-1H-1,2,4-triazol-5-yl)thio)acetonitrile (CAS 61691-03-0)
- 2-(2-Amino-5-fluoropyridin-3-yl)acetic acid (CAS 1805099-05-1)
- 4-(1H-Benzimidazol-2-yl)-1-(4-ethoxyphenyl)pyrrolidin-2-one (CAS 615281-70-4)
- n-(Tert-butyl)-1-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxamide (CAS 1280875-13-9)
- 252976-51-5 Trifluoromethanesulfonic acid ytterbium salt Yb(OTf)3 Ytterbium(III) triflate Ytterbium(III) trifluoromethanesulfonate hydrate (CAS 252976-51-5)
- 1-Furan-2-yl-2-[(2-hydroxy-ethyl)-isopropyl-amino]-ethanone (CAS 1250918-91-2)
- 5-(Benzyloxy)-3-iodo-1H-indazole (CAS 854632-98-7)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com