Raloxifene Impurity 22 CAS 166975-60-6
| CAS No. | 166975-60-6 |
| Molecular Formula | C23H18O8S3 |
| Molecular Weight | 518.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Raloxifene Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Raloxifene Impurity 22 (CAS 166975-60-6), a pharmacopoeial impurity reference standard (molecular formula C23H18O8S3, MW 518.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, Raloxifene Impurity 22 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 518.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H18O8S3 |
| Molecular Weight | 518.58 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Sulfur Atoms | 3 |
Related Raloxifene Standards
- Raloxifene Impurity 10 (CAS CATO-C4X-174310)
- Raloxifene-d4 Bismethyl Ether (CAS 1185006-58-9)
- Raloxifene Impurity 11 (CAS CATO-C4X-174311)
- Raloxifene Bismethyl ether (CAS 84541-38-8)
- Raloxifene Impurity 12 (CAS CATO-C4X-174312)
- Raloxifene EP Impurity C (CAS 195454-31-0)
- Raloxifene 6-Monomethyl Ether (CAS 178451-13-3)
- Raloxifene 4-Monomethyl Ether (CAS 185415-07-0)
Recommended Standards
- Meropenem Impurity 13 (CAS CATO-C4X-130913)
- 3,4-Bis(2,5,8,11-tetraoxatridecan-13-yloxy)benzaldehyde (CAS 109168-95-8)
- Vonoprazan Impurity 230 (CAS CATO-C4X-1020230)
- N-((5-((2-(Benzo[d]thiazol-2-ylamino)-2-oxoethyl)thio)-4-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl)methyl)benzamide (CAS 393839-63-9)
- Nafamostat impurity 77 (CAS CATO-C4X-133277)
- Nafamostat impurity 127 (CAS CATO-C4X-1332127)
- Digoxin EP Impurity B (CAS 4562-36-1)
- N,N-Diisopropyl-3-(2-methoxy-5-methyl-phenyl)-3-phenylpropylamine-d14 (CAS 1795031-80-9)
- N-(4-Fluorophenyl)(tert-butoxy)carbohydrazide (CAS 1075749-75-5)
- Aglepristone (CAS 124478-60-0)
- Ethyl 5-(methylsulfonamido)-1H-indole-2-carboxylate (CAS 179556-14-0)
- 2-(4-Methoxyphenyl)quinazoline-4-carboxylic acid (CAS 925931-92-6)
- (S)-3-Isobutylpiperazin-2-one (CAS 527706-40-7)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
Why CATO?
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