Ketorolac EP Impurity E CAS 167105-80-8
| CAS No. | 167105-80-8 |
| Molecular Formula | C19H22N2O5 |
| Molecular Weight | 358.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ketorolac EP Impurity E is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ketorolac EP Impurity E (CAS 167105-80-8) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22N2O5 and a molecular weight of 358.39 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Ketorolac EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 358.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ketorolac EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O5 |
| Molecular Weight | 358.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 2 |
Related Ketorolac Standards
- Ketorolac Impurity 59 (CAS 2705552-46-9)
- Ketorolac impurity 64 (CAS 141031-78-9)
- Ketorolac Impurity 37 (CAS CATO-C4X-166937)
- Ketorolac Impurity 29 (CAS CATO-C4X-166929)
- Ketorolac Impurity 79 (CAS CATO-C4X-166979)
- Ketorolac Impurity 71 (CAS CATO-C4X-166971)
- Ketorolac Impurity 46 (CAS 144710-34-9)
- Ketorolac Impurity 47 (CAS CATO-C4X-166947)
Recommended Standards
- Atenolol EP Impurity E (CAS 141650-31-9)
- Naltrexone impurity 56 (CAS CATO-C4X-147556)
- Ceftizoxime Impurity 65 (CAS CATO-C4X-179365)
- Tirofiban Impurity 77 (CAS 13022-41-8)
- Rebamipide Impurity 7 (CAS 90098-08-1)
- Arbidol Impurity 15 (CAS CATO-C4X-112915)
- Lamivudine EP impurity A (CAS 173602-25-0)
- 5-Benzylpyridin-2-amine (CAS 98477-40-8)
- 2-(1H-1,2,4-Triazol-3-yl)acetic Acid Hydrochloride (CAS 1087714-25-7)
- (2S)-2-amino-2-(2,5-dichlorophenyl)ethan-1-ol hydrochloride (CAS 1391487-11-8)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
- 5-Bromo-1-cyclopentyl-1H-pyrazole (CAS 1368151-58-9)
- 1-Chloro-2,2,2-trifluoroethane-1-sulfonyl chloride (CAS 885460-96-8)
- Peptide 437 (CAS CATO-CPTD788437)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com