Metformin EP Impurity E HCl CAS 1674-62-0
| CAS No. | 1674-62-0 |
| Molecular Formula | C3H9N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metformin EP Impurity E HCl.
CATO supplies Metformin EP Impurity E HCl (CAS 1674-62-0), a pharmacopoeial impurity reference standard (molecular formula C3H9N5HCl, MW 151.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Metformin EP Impurity E HCl (C3H9N5HCl) contains chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H9N5 HCl |
| Molecular Weight | 151.60 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Metformin Standards
- Metformin EP Impurity D (CAS 108-78-1)
- Metformin Hydrochloride (CAS 1115-70-4)
- Metformin-d6 Hydrochloride (CAS 1185166-01-1)
- Metformin Impurity 38 (CAS 118632-64-7)
- Metformin EP impurity F Tetrahydrofuran Solution (CAS 124-40-3 (free base))
- Metformin Impurity 532 (CAS 141-83-3)
- Metformin Impurity N74 (CAS 1609-00-3)
- Metformin Impurity 27 (CAS 18240-93-2)
Recommended Standards
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- Ethyl 2-(2-(but-3-yn-1-yl)-1,3-dioxolan-2-yl)acetate (CAS 91798-91-3)
- 6-Methyl-4-propyl-4,5-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 115699-81-5)
- (2,4-Dibromo-5-methoxyphenyl)methanol (CAS 2386293-45-2)
- 3,4-Diphenyl-5,6,7,8-tetrahydrocinnoline (CAS 854891-63-7)
- Relugolix Impurity 163 (CAS CATO-C4X-2429163)
- N-(6-chloropyridin-3-yl)-2-methylbenzenesulfonamide (CAS 1296172-32-1)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com