Metformin-d6 Hydrochloride CAS 1185166-01-1
| CAS No. | 1185166-01-1 |
| Molecular Formula | - |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Metformin-d6 Hydrochloride is closely related to deuterium isotope labeling, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Metformin-d6 Hydrochloride (CAS 1185166-01-1), molecular formula C4H5D6N5HCl and molecular weight 171.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Metformin-d6 Hydrochloride (C4H5D6N5HCl) is characterized by deuterium isotope labeling, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Metformin-d6 Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H5D6N5 HCl |
| Molecular Weight | 171.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Metformin Standards
- Metformin EP Impurity D (CAS 108-78-1)
- Metformin Hydrochloride (CAS 1115-70-4)
- Metformin Impurity 38 (CAS 118632-64-7)
- Metformin EP impurity F Tetrahydrofuran Solution (CAS 124-40-3 (free base))
- Metformin Impurity 532 (CAS 141-83-3)
- Metformin Impurity N74 (CAS 1609-00-3)
- Metformin EP Impurity E HCl (CAS 1674-62-0)
- Metformin Impurity 27 (CAS 18240-93-2)
Recommended Standards
- Raltegravir-d3 Potassium Salt (CAS 1246816-98-7)
- 3-Phenoxy-6-phenylpyridazine-4-carbonitrile (CAS 338751-72-7)
- 4-(Benzo[d][1,3]dioxol-5-yl)butanoic acid (CAS 41303-44-0)
- 2,4-Dichloro-5,6,7,8-tetrahydro-5,8-methanoquinoline-3-carbonitrile (CAS 2768871-83-4)
- N-Methylhydrazinecarboxamide Hydrochloride (CAS 4140-62-9)
- 4-(1H-Imidazol-5-yl)-1,2,3,6-tetrahydropyridine (CAS 273218-94-3)
- Aminooxy-PEG4-CH2-Boc (CAS 2062663-62-9)
- Abscisic Acid (CAS 14375-45-2)
- Ixazomib Impurity 48 (CAS CATO-C4X-126748)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
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