(2-(Chloromethyl)phenyl)diphenylphosphane CAS 167706-40-3
| CAS No. | 167706-40-3 |
| Molecular Formula | C19H16ClP |
| Molecular Weight | 310.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2-(Chloromethyl)phenyl)diphenylphosphane is closely related to organophosphorus functionality, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2-(Chloromethyl)phenyl)diphenylphosphane (CAS 167706-40-3), molecular formula C19H16ClP and molecular weight 310.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-(Chloromethyl)phenyl)diphenylphosphane (C19H16ClP) is characterized by organophosphorus functionality, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-(Chloromethyl)phenyl)diphenylphosphane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16ClP |
| Molecular Weight | 310.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
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- 2-(chloromethyl)-3-(2-oxopropyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one (CAS 743445-03-6)
- 1-(Chloromethyl)-4-(dodecyloxy)benzene (CAS 118468-30-7)
- Methyl 3-(chloromethyl)-5-iodobenzoate (CAS 1393566-98-7)
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Recommended Standards
- N-(2-Chlorophenyl)-5-(methylsulfonyl)picolinamide (CAS 1380672-71-8)
- 2-Chloro-N-(3-nitro-phenyl)-N-thiophen-2-ylmethyl-acetamide (CAS 333778-31-7)
- N'-((6-(4-Chlorophenoxy)pyrimidin-4-yl)thio)acetohydrazide (CAS 137927-75-4)
- 2-Chloro-N-(3-sulfamoyl-phenyl)-benzamide (CAS 303126-57-0)
- [6-(2,5-dimethylphenoxy)pyridin-3-yl]methylamine (CAS 954260-72-1)
- 5-Bromo-4-fluoro-2-methylbenzonitrile (CAS 1695413-38-7)
- 7-Chloro-3-(1-methylpiperidin-4-yl)-1H-indole (CAS 734518-22-0)
- Boc-(4-piperidino)-Pro-OH (CAS 221352-39-2)
- 1-Boc-5-(methoxycarbonyl)piperidine-2-carboxylic Acid (CAS 1416371-93-1)
- S-(4-Bromophenyl) ethanethioate (CAS 28122-76-1)
- 6-Oxa-2-azabicyclo[3.2.1]octane (CAS 279-98-1)
- 2-((4-Hydroxy-4-(pyridin-3-yl)butyl)amino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (CAS 502507-70-2)
- 1-((4-Chlorophenyl)sulfonyl)cyclobutane-1-carboxylic acid (CAS 879361-76-9)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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