1,4-Bis(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)benzene CAS 257880-89-0

Purity 97%+In StockPharmaceutical Standards
CAS No.257880-89-0
Molecular FormulaC12H8Cl2N4O2
Molecular Weight311.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,4-Bis(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)benzene CAS 257880-89-0 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1,4-Bis(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)benzene (CAS 257880-89-0) is a high-purity analytical reference standard with the molecular formula C12H8Cl2N4O2 and a molecular weight of 311.12 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1,4-Bis(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)benzene is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H8Cl2N4O2
Molecular Weight311.12 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms4

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