Trifluoro-methanesulfonic acid ethyldimethylsilyl ester CAS 1680176-27-5
| CAS No. | 1680176-27-5 |
| Molecular Formula | C5H11F3O3SSi |
| Molecular Weight | 236.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trifluoro-methanesulfonic acid ethyldimethylsilyl ester is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Trifluoro-methanesulfonic acid ethyldimethylsilyl ester (CAS 1680176-27-5) is a high-purity analytical reference standard with the molecular formula C5H11F3O3SSi and a molecular weight of 236.28 g/mol.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Trifluoro-methanesulfonic acid ethyldimethylsilyl ester is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H11F3O3SSi |
| Molecular Weight | 236.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -1.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Trifluoro Standards
- 1,1,1-Trifluoro-11-dodecene-2-one (CAS 141023-04-3)
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- 4,4,4-Trifluoro-2-methyl-1-(thiophen-2-yl)butane-1,3-dione (CAS 346-01-0)
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Recommended Standards
- 2,3-Difluoro-4'-methylsulfanylbiphenyl (CAS 157248-20-9)
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- (Trimethylsilyl)methyl Trifluoromethanesulfonate [Trimethylsilylmethylating Reagent] (CAS 64035-64-9)
- 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-methyl-3-nitrophenyl)acetamide (CAS 337498-67-6)
- 3,4-Dibromo-5-nitrotertbutylbenzene (CAS 57716-71-9)
- tert-Butyl 2-acetyl-1H-pyrrole-1-carboxylate (CAS 75400-61-2)
- 2-Bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-phenylacetamide (CAS 864932-47-8)
- (2-Methylpentanoyl)-d-valine (CAS 1189191-17-0)
- 1,3-Bis[4-(trifluoromethyl)phenyl]thiourea (CAS 1744-07-6)
- Etrasimod Impurity 49 (CAS 1788895-59-9)
- 4-Formylnaphthalene-1-carboxylic acid (CAS 219685-15-1)
- 2-[(4-Bromophenyl)sulfanyl]-6-phenylpyridine-3-carbonitrile (CAS 252058-87-0)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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