Etrasimod Impurity 49 CAS 1788895-59-9
| CAS No. | 1788895-59-9 |
| Molecular Formula | C25H26F6 |
| Molecular Weight | 440.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Etrasimod Impurity 49 (CAS 1788895-59-9), a pharmacopoeial impurity reference standard (molecular formula C25H26F6, MW 440.46 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Etrasimod Impurity 49 (C25H26F6) is characterized by fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H26F6 |
| Molecular Weight | 440.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related Etrasimod Standards
- Etrasimod Impurity 59 (CAS CATO-C4X-321459)
- Etrasimod Impurity 41 (CAS 2863532-92-5)
- Etrasimod (CAS 1206123-37-6)
- Etrasimod impurity 2 (CAS 1206123-51-4)
- Etrasimod Impurity 50 (CAS CATO-C4X-321450)
- Etrasimod Impurity 69 (CAS CATO-C4X-321469)
- Etrasimod Impurity 9 (CAS 1206123-55-8)
- Etrasimod Impurity 13 (CAS CATO-C4X-321413)
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