4-Fluoro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one CAS 168163-93-7
| CAS No. | 168163-93-7 |
| Molecular Formula | C17H16FNO3S |
| Molecular Weight | 333.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Fluoro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one (CAS 168163-93-7), molecular formula C17H16FNO3S and molecular weight 333.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Fluoro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one (C17H16FNO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4-Fluoro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16FNO3S |
| Molecular Weight | 333.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Tas-103 (CAS 174634-08-3)
- 6-Benzyloxyindole-3-carbaldehyde (CAS 92855-64-6)
- JWH 412 (CAS 1364933-59-4)
- 3-(Pyrrolidin-3-yl)-1H-pyrazole (CAS 1225218-82-5)
- (E)-N'-{5-[(3,4-dimethylphenyl)amino]-1H-1,2,4-triazol-3-yl}-N,N-dimethylmethanimidamide (CAS 328287-36-1)
- Moxidectin EP Impurity F (CAS CATO-C4X-227510)
- (2R)-2-[3-(2-methoxyethoxy)-5-oxo-1,6-naphthyridin-6-yl]propanoic acid;naphthalene-2-sulfonic acid (CAS 1643590-80-0)
- 5-Aminobenzoxazole-2-thiol (CAS 24316-85-6)
- 2-[2-(2-chlorophenyl)-1,3-thiazol-4-yl]ethan-1-amine (CAS 938377-76-5)
- 2-(Chloromethyl)-5-(difluoromethoxy)benzo[d]oxazole (CAS 1803855-42-6)
- Semaglutide (CAS 910463-68-2（free base）)
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