Tirofiban Impurity 33 CAS 16870-43-2
| CAS No. | 16870-43-2 |
| Molecular Formula | C9H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tirofiban Impurity 33.
Tirofiban Impurity 33 (CAS 16870-43-2) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11NO3HCl and a molecular weight of 217.65 g/mol.
Structurally, Tirofiban Impurity 33 (C9H11NO3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 217.65 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tirofiban Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11NO3 HCl |
| Molecular Weight | 217.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tirofiban Standards
- Tirofiban Impurity 111 (CAS 100-43-6)
- Tirofiban Impurity 26 (CAS 102878-73-9)
- Tirofiban Impurity 65 (CAS 109315-44-8)
- Tirofiban Impurity 108 (CAS 1103300-75-9)
- Tirofiban Impurity 77 (CAS 13022-41-8)
- Tirofiban-d9 Hydrochloride (CAS 1331911-68-2)
- Tirofiban Impurity 122 (CAS 13344-50-8)
- Tirofiban Impurity 118 (CAS 1346918-32-8)
Recommended Standards
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Salicylic Acid Impurity 20 (CAS CATO-C4X-190220)
- Efavirenz Impurity 5 (CAS 1189491-03-9)
- 1,3,5-Trimethyl-1H-pyrazole-4-carboxylic Acid (CAS 1125-29-7)
- Methyl 3-[4-(ethylcarbamoyl)-3-fluorophenyl]-2-fluorobenzoate (CAS 1381944-66-6)
- 3-(1,3-Dioxan-2-yl)-1-(4-methoxyphenyl)propan-1-one (CAS 121789-38-6)
- 4-Amino-2-(hydroxymethyl)pyridine (CAS 100114-58-7)
- 4-Ethyl-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 865659-97-8)
- 2-Iodo-3,5-diphenylpyridine (CAS 873913-82-7)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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