Sotalol EP Impurity A HCl CAS 16974-44-0
| CAS No. | 16974-44-0 |
| Molecular Formula | C12H20N2O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Sotalol EP Impurity A HCl is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 292.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Sotalol EP Impurity A HCl (CAS 16974-44-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H20N2O2SHCl and a molecular weight of 292.82 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sotalol EP Impurity A HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H20N2O2S HCl |
| Molecular Weight | 292.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Sotalol Standards
Recommended Standards
- Mianserin Impurity 19 (CAS 62510-46-7)
- Fluralaner Impurity 16 (CAS 1437051-93-8)
- Rosuvastatin Impurity 107 (CAS 122549-26-2)
- 4,8-Dihydroxycoumarin (CAS 106754-20-5)
- 2-(4-Acetylpiperazin-1-yl)-4-chlorothiazole-5-carbaldehyde (CAS 914348-66-6)
- 3,5-Dihydroxybenzohydrazide (CAS 7732-32-3)
- 4-(Tert-butoxycarbonyl)hexahydro-2H-furo[3,2-b]pyrrole-6-carboxylic acid (CAS 1936631-17-2)
- 4-(1-(4-Chlorophenoxy)ethyl)pyrimidin-2-amine (CAS 339021-08-8)
- 4-(2,2,2-Trifluoroethyl)benzonitrile (CAS 1198117-92-8)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com