7-bromo-6-chloro-2-(chloromethyl)-8-fluoroquinazolin-4-ol CAS 1698028-16-8
| CAS No. | 1698028-16-8 |
| Molecular Formula | C9H14BrCl2FN2O |
| Molecular Weight | 336.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-bromo-6-chloro-2-(chloromethyl)-8-fluoroquinazolin-4-ol (C9H14BrCl2FN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 7-bromo-6-chloro-2-(chloromethyl)-8-fluoroquinazolin-4-ol (CAS 1698028-16-8), a certified reference material (molecular formula C9H14BrCl2FN2O, MW 336.03 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14BrCl2FN2O |
| Molecular Weight | 336.03 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
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