Adefovir Impurity 5 CAS 116384-53-3
| CAS No. | 116384-53-3 |
| Molecular Formula | C12H20N5O4P |
| Molecular Weight | 329.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Adefovir Impurity 5 (CAS 116384-53-3), a pharmacopoeial impurity reference standard (molecular formula C12H20N5O4P, MW 329.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Adefovir Impurity 5 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H20N5O4P |
| Molecular Weight | 329.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 5 |
Related Adefovir Standards
- Adefovir Dipivoxil Impurity 32 (CAS 374678-38-3)
- Adefovir Impurity 37 (CAS CATO-C4X-115237)
- Adefovir Impurity 6 (CAS 116384-54-4)
- Adefovir Impurity 21 (CAS CATO-C4X-115221)
- Adefovir Impurity 22 (CAS CATO-C4X-115222)
- Adefovir Dipivoxil Impurity 41 (CAS 107021-27-2)
- Adefovir Dipivoxil Impurity 35 (CAS 374678-39-4)
- Adefovir (CAS 106941-25-7)
Recommended Standards
- Tenofovir Impurity 64 (CAS CATO-C4X-107664)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com