6-Bromo-2-chloropyridin-3-amine CAS 169833-70-9
| CAS No. | 169833-70-9 |
| Molecular Formula | C5H4BrClN2 |
| Molecular Weight | 207.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Bromo-2-chloropyridin-3-amine is closely related to a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-Bromo-2-chloropyridin-3-amine (CAS 169833-70-9), a certified reference material (molecular formula C5H4BrClN2, MW 207.46 g/mol) for analytical method development and quality control.
Structurally, 6-Bromo-2-chloropyridin-3-amine (C5H4BrClN2) contains a nitrile group, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 207.46 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Bromo-2-chloropyridin-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4BrClN2 |
| Molecular Weight | 207.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-5-chloropyridin-2-amine (CAS 1004294-58-9)
- 2-Bromo-6-chloropyridin-3-amine (CAS 1050501-88-6)
- 2-Bromo-6-chloropyridin-4-amine (CAS 1060815-59-9)
- 2-Bromo-5-chloropyridin-4-amine (CAS 1060815-72-6)
- 6-Bromo-3-chloropyridin-2-amine (CAS 1060815-73-7)
- 4-Bromo-2-chloro-6-methylpyrimidine (CAS 1137576-45-4)
- 4-Bromo-6-chloropyridin-2-amine (CAS 1206250-19-2)
- 2-Bromo-5-chloro-3-methylpyrazine (CAS 1260664-82-1)
Recommended Standards
- 5-(bromomethyl)-2-chloro-pyrimidine (CAS 153281-13-1)
- 2-Bromo-3-chloro-5-methylpyrazine (CAS 1783607-43-1)
- 4-Bromo-6-chloropyridin-3-amine (CAS 1449239-58-0)
- 4-Bromo-5-chloropyridin-3-amine (CAS 1802434-30-5)
- 5-Bromo-6-azaindole-3-carbaldehyde (CAS 1369348-93-5)
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