4'-Carboxybenzo-12-crown-4 CAS 170031-43-3
| CAS No. | 170031-43-3 |
| Molecular Formula | C13H16O6 |
| Molecular Weight | 268.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4'-Carboxybenzo-12-crown-4 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4'-Carboxybenzo-12-crown-4 (CAS 170031-43-3), a certified reference material (molecular formula C13H16O6, MW 268.26 g/mol) for analytical method development and quality control.
The molecular framework of 4'-Carboxybenzo-12-crown-4 (C13H16O6) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4'-Carboxybenzo-12-crown-4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16O6 |
| Molecular Weight | 268.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
Related Carboxybenzo Standards
Recommended Standards
- 4,6-Bis(4-fluorophenyl)pyrimidine (CAS 168915-00-2)
- (5-Hydroxybenzofuran-3-yl)(4-methoxyphenyl)methanone (CAS 17249-65-9)
- 3-(Benzo[d][1,3]dioxol-5-yl)-1-(2-hydroxyphenyl)prop-2-en-1-one (CAS 16669-99-1)
- 1-Hydroxy-2-(methoxymethyl)anthracene-9,10-dione (CAS 174568-52-6)
- 4-Ethyl-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1404367-85-6)
- 1-(1-Naphthyl)cyclobutanecarboxylic Acid (CAS 59725-63-2)
- 2-Bromoquinolin-7-amine (CAS 1783789-94-5)
- (4-Amino-2-methylquinolin-3-yl)methanol (CAS 75353-57-0)
- 7-Methylbenzo[d]thiazole-2-thiol, 97% (CAS 54237-36-4)
- 4-Amino-6-(tert-butyl)-1-methyl-1,3,5-triazin-2(1H)-one (CAS 175204-73-6)
- 2-(Pyridin-3-ylamino)acetonitrile (CAS 62491-93-4)
- (1-Ethyl-5-methyl-1H-pyrazol-4-yl)methanol (CAS 494214-31-2)
- (Z)-2-((4-chlorophenyl)thio)-N'-hydroxynicotinimidamide (CAS 886360-64-1)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com