4-Fluoro-3-methoxy-5-(trifluoromethyl)phenylboronic acid CAS 1701449-45-7
| CAS No. | 1701449-45-7 |
| Molecular Formula | C8H7BF4O3 |
| Molecular Weight | 237.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Fluoro-3-methoxy-5-(trifluoromethyl)phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Fluoro-3-methoxy-5-(trifluoromethyl)phenylboronic acid (CAS 1701449-45-7) is a high-purity analytical reference standard with the molecular formula C8H7BF4O3 and a molecular weight of 237.94 g/mol.
Structurally, 4-Fluoro-3-methoxy-5-(trifluoromethyl)phenylboronic acid (C8H7BF4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 237.94 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7BF4O3 |
| Molecular Weight | 237.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (5-Fluoro-2-(2,2,2-trifluoroethoxy)phenyl)boronic acid (CAS 1313760-94-9)
- 3-Fluoro-4-methoxy-5-trifluoromethylphenylboronic acid (CAS 1451391-99-3)
- 2-Fluoro-5-methoxy-3-(trifluoromethyl)phenylboronic acid (CAS 1772622-44-2)
- (2-Fluoro-3-(2,2,2-trifluoroethoxy)phenyl)boronic acid (CAS 855230-62-5)
- (3-Fluoro-4-(2,2,2-trifluoroethoxy)phenyl)boronic acid (CAS 947533-09-7)
- (3-Fluoro-5-(2,2,2-trifluoroethoxy)phenyl)boronic acid (CAS 850589-55-8)
- (4-Fluoro-3-(2,2,2-trifluoroethoxy)phenyl)boronic acid (CAS 957034-62-7)
- [2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid (CAS 2246556-71-6)
Recommended Standards
- (4-(1,1,2,2-Tetrafluoroethoxy)phenyl)boronic acid (CAS 1254118-45-0)
- (3-(2,2-Difluoroethoxy)-4,5-difluorophenyl)boronic acid (CAS 936250-23-6)
- 5-CHLORO-3-(TRICHLOROMETHYL)-1,2,4-THIADIAZOLE (CAS 5848-93-1)
- Bromomethanesulfonyl Bromide (CAS 54730-18-6)
- Azetidine-3-carboxylic acid cyclopropylmethyl-amide trifluoroacetic acid salt (CAS 1361113-16-7)
- Methyl 4-((phenethylamino)methyl)benzoate (CAS 851365-09-8)
- (3-(3-(4-Ethylpiperazin-1-yl)propoxy)-4-methylphenyl)boronic acid (CAS 1704064-34-5)
- 2-Bromo-6-methoxy-1-methyl-5-(trifluoromethyl)naphthalene (CAS 122670-67-1)
- Bromodifluoromethane (CAS 1511-62-2)
- N-[1-(4-Allyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-ethyl]-benzamide (CAS 792941-55-0)
- 4-[(4-Fluorophenyl)methyl]-3-[1-(5-methylthiophene-2-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775311-16-4)
- Cyclopropanecarbonyl cyanide (CAS 6047-92-3)
- 3-Bromo-6-fluoro-2-nitrophenylacetic acid (CAS 1807183-06-7)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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