[2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid CAS 2246556-71-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid.

[2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid (CAS 2246556-71-6) is a high-purity analytical reference standard with the molecular formula C8H7BF4O3 and a molecular weight of 237.94 g/mol.

The molecular framework of [2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]boronic acid (C8H7BF4O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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