2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine CAS 170309-05-4

Purity 97%+In StockPharmaceutical Standards
CAS No.170309-05-4
Molecular FormulaC7H5ClN4O2
Molecular Weight212.59 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine CAS 170309-05-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 212.59 g/mol gives 2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine (CAS 170309-05-4), molecular formula C7H5ClN4O2 and molecular weight 212.59 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine (C7H5ClN4O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H5ClN4O2
Molecular Weight212.59 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2005
Halogen ContentCl-containing
Nitrogen Atoms4

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