2-(Chloromethyl)-6-nitrobenzo[d]oxazole CAS 221638-74-0
| CAS No. | 221638-74-0 |
| Molecular Formula | C8H5ClN2O3 |
| Molecular Weight | 212.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Chloromethyl)-6-nitrobenzo[d]oxazole (C8H5ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(Chloromethyl)-6-nitrobenzo[d]oxazole (CAS 221638-74-0) is a high-purity analytical reference standard with the molecular formula C8H5ClN2O3 and a molecular weight of 212.59 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Chloromethyl)-6-nitrobenzo[d]oxazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O3 |
| Molecular Weight | 212.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-5-nitro-1,3-benzoxazole (CAS 119198-10-6)
- 2-(Chloromethyl)-4-nitrobenzo[d]oxazole (CAS 143708-26-3)
- 2-(Chloromethyl)-7-nitrobenzo[d]oxazole (CAS 1540115-47-6)
- 2-(Chloromethyl)-3-nitroimidazo[1,2-a]pyrimidine (CAS 170309-05-4)
- 5-(Chloromethyl)-1-ethyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1171086-33-1)
- 3-(Chloromethyl)-1-ethyl-5-(trifluoromethyl)-1H-pyrazole (CAS 1260659-15-1)
- 2-(Chloromethyl)-1-fluoro-3-(trifluoromethyl)benzene (CAS 1001096-10-1)
- 5-(Chloromethyl)-1-(3-fluorophenyl)-1h-1,2,3,4-tetrazole (CAS 1105194-91-9)
Recommended Standards
- 2-(6-chloro-9H-purin-9-yl)acetic acid (CAS 56763-07-6)
- 3-Chloro-5-nitro-1H-indazol-7-amine (CAS 647853-24-5)
- 7-chloro-5-methyl-6H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1935530-73-6)
- 4-Chloro-5-methyl-5,8-dihydropteridine-6,7-dione (CAS 2718971-76-5)
- Pterosin Z (CAS 34169-69-2)
- 6-Chloro-5-methoxy-indolin (CAS 1369041-89-3)
- Misoprostol EP Impurity F (CAS 40098-26-8)
- 4-N-Butoxyphenylacetic Acid (CAS 4547-57-3)
- (E)-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)acrylic acid (CAS 387350-55-2)
- 9-(4,6-Diphenyl-1,3,5-triazin-2-yl)-9'-phenyl-9H,9'H-3,3'-bicarbazole (CAS 1266389-01-8)
- 14,14-Dimethyl-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6-tetraen-12-one (CAS 39222-65-6)
- 2-Propenoic acid, polymer with butyl 2-propenoate and ethyl 2-propenoate (CAS 27322-15-2)
- 2-Amino-5-cyclopropylbenzonitrile (CAS 660862-01-1)
- Eledoisin Related Peptide (CAS 2990-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com