3-Phenyl-1,4-dioxane-2-carboxylic acid CAS 1706443-88-0
| CAS No. | 1706443-88-0 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Phenyl-1,4-dioxane-2-carboxylic acid (CAS 1706443-88-0) is a high-purity analytical reference standard with the molecular formula C11H12O4 and a molecular weight of 208.21 g/mol.
The molecular framework of 3-Phenyl-1,4-dioxane-2-carboxylic acid (C11H12O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
Related Phenyl Standards
- 5-Phenyl-1,4-dioxane-2-carboxylic acid (CAS 1263281-01-1)
- 2-Phenyl-1,3-dioxane-5-carboxylic acid (CAS 150994-99-3)
- 2-phenyl-1,3-dioxane-4-carboxylic acid (CAS 178680-96-1)
- 1,3-Dioxane, 4-(bromomethyl)-2,2-dimethyl-, (4S)- (CAS 191354-56-0)
- 1,3-Dioxane-5-carboxylic acid, 5-methyl-2-oxo-, 2-propenyl ester 532424-75-2 (CAS 532424-75-2)
- 4-Phenyl-1,3-dioxane (CAS 772-00-9)
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- 1,3-Dioxane-5,5-dimethanol (CAS 6228-25-7)
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