3-(4-Chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine CAS 439107-57-0
| CAS No. | 439107-57-0 |
| Molecular Formula | C19H14ClFN4 |
| Molecular Weight | 352.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 439107-57-0), molecular formula C19H14ClFN4 and molecular weight 352.79 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H14ClFN4, 3-(4-Chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 352.79 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H14ClFN4 |
| Molecular Weight | 352.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chlorophenyl Standards
- 2-((4-Chlorophenyl)thio)-N-(2-methoxy-5-nitrophenyl)acetamide (CAS 461399-66-6)
- 3-(2-Chlorophenyl)-N-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 890635-53-7)
- 3-(3-Chlorophenyl)-5-((2,6-difluorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 578698-20-1)
- 3-(4-Chlorophenyl)-5-((2,6-difluorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 577790-80-8)
- 4-[2-(4-Chlorophenyl)acetyl]-8-methyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-38-1)
- 3-(((4-Chlorophenyl)imino)methyl)-2-hydroxy-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinolin-4-one (CAS 338953-30-3)
- 4-[3-(4-Chlorophenyl)-4,5,6,7-tetrahydro-2H-indazol-2-yl]benzoic acid (CAS 861210-33-5)
- N-(4-chlorophenyl)-1,4,9-trioxa-12-azadispiro[4.2.4(8).2(5)]Tetradecane-12-carboxamide (CAS 861209-91-8)
Recommended Standards
- 3-Iodothiophene-2-carboxylic acid (CAS 676995-91-8)
- N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-chloro-2-methylaniline (CAS 321433-85-6)
- Cefaclor Impurity 48 (CAS CATO-C4X-127048)
- Chlorthalidone impurity 20 (CAS 96512-76-4)
- N-(3-(1H-Imidazol-1-yl)propyl)methanesulfonamidehydrochloride (CAS 1198416-83-9)
- 6-Chloro-N-(4-methoxybenzyl)-5-nitropyrimidin-4-amine (CAS 651013-61-5)
- 4-oxo-3H-quinazoline-6-carboxamide (CAS 150454-06-1)
- Trimethyl({[4-(trimethylsilyl)but-3-yn-1-yl]oxy})silane (CAS 58434-99-4)
- 1-Bromo-3-fluoro-2-methoxy-5-methylbenzene (CAS 1394291-45-2)
- 3-(2,2,3,3-Tetramethylcyclopropyl)isoxazol-5-amine (CAS 1520954-44-2)
- 2-(Dimethylphosphoryl)acetonitrile (CAS 89630-50-2)
- Atogepant Impurity 26 (CAS 957122-44-0)
- 4-Chloro-N-(5,6-dimethyl-1-propyl-1H-1,3-benzodiazol-4-yl)benzene-1-sulfonamide (CAS 338423-73-7)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
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