4-Chloro-6-(difluoromethyl)-5-nitropyrimidine CAS 1706458-47-0
| CAS No. | 1706458-47-0 |
| Molecular Formula | C5H2ClF2N3O2 |
| Molecular Weight | 209.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C5H2ClF2N3O2, 4-Chloro-6-(difluoromethyl)-5-nitropyrimidine contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 209.54 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Chloro-6-(difluoromethyl)-5-nitropyrimidine (CAS 1706458-47-0), molecular formula C5H2ClF2N3O2 and molecular weight 209.54 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-6-(difluoromethyl)-5-nitropyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2ClF2N3O2 |
| Molecular Weight | 209.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-2,6-difluoro-5-nitropyridin-4-amine (CAS 405230-89-9)
- 2-Chloro-3,4,5,6-Tetrafluoro-Benzonitrile (CAS 126817-44-5)
- 6-Chloro-4-(trifluoromethyl)nicotinaldehyde (CAS 1005171-96-9)
- 3-Chloro-2,4,5-trifluorobenzamide (CAS 101513-85-3)
- 6-Chloro-4-(trifluoromethyl)pyridine-2-carboxaldehyde (CAS 1060805-47-1)
- 4-Chloro-6-(trifluoromethyl)picolinaldehyde (CAS 1060807-45-5)
- 2-Chloro-6-(trifluoromethyl)isonicotinaldehyde (CAS 1060807-47-7)
- 4-Chloro-6-(trifluoromethyl)pyridine-3-carbaldehyde (CAS 1060807-48-8)
Recommended Standards
- Montelukast Impurity 57 (CAS 30220-25-8)
- a,a,a-Trichloro-o-xylene (CAS 3335-33-9)
- 4-Chloro-1,2-bis(chloromethyl)benzene (CAS 212755-99-2)
- 4-(Trifluoromethyl)nicotinoyl chloride (CAS 104326-73-0)
- 6,6'-Diiodo-9,9'-diphenyl-9H,9'H-3,3'-bicarbazole (CAS 57102-64-4)
- 2-(benzylamino)-3,3,3-trifluoro-2-methylpropanenitrile (CAS 1260983-08-1)
- 2-(2,3-Dihydro-1-benzofuran-6-yl)ethan-1-ol (CAS 1504762-91-7)
- 1-Nitro-4-(thiocyanatomethyl)benzene (CAS 13287-49-5)
- (3-(3-Methoxypropoxy)phenyl)boronic acid (CAS 863252-62-4)
- 2-(2-methyl-1H-imidazol-1-yl)isonicotinonitrile (CAS 1016841-67-0)
- 2,1,3-benzoxadiazol-5-amine (CAS 874-36-2)
- 2-Benzenesulfonamidohexanoic acid (CAS 108244-71-9)
- (2S)-3-Amino-2-(4-methylphenyl)propanoic acid (CAS 1260684-80-7)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com