Montelukast Impurity 57 CAS 30220-25-8
| CAS No. | 30220-25-8 |
| Molecular Formula | C8H7Cl3 |
| Molecular Weight | 209.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Montelukast Impurity 57 (CAS 30220-25-8, C8H7Cl3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to chlorine substitution, an aromatic ring system, Montelukast Impurity 57 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 209.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Montelukast Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7Cl3 |
| Molecular Weight | 209.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
Related Montelukast Standards
- Montelukast Impurity N4 (CAS 855473-50-6)
- Montelukast Impurity 55 (CAS 152922-86-6)
- Montelukast Impurity 9 (CAS 30430-40-1)
- Montelukast Impurity 48 (CAS 87764-54-3)
- Montelukast Impurity 21 (CAS 152922-72-0)
- Montelukast Impurity N6 (CAS 66-40-0)
- Montelukast Impurity N27 (CAS 610-97-9)
- Montelukast Impurity 54 (CAS 89729-09-9)
Recommended Standards
- a,a,a-Trichloro-o-xylene (CAS 3335-33-9)
- 2-Chloro-3,4,5,6-Tetrafluoro-Benzonitrile (CAS 126817-44-5)
- 4-Chloro-1,2-bis(chloromethyl)benzene (CAS 212755-99-2)
- 4-Chloro-6-(difluoromethyl)-5-nitropyrimidine (CAS 1706458-47-0)
- Galanthamine Impurity 27 (CAS CATO-C4X-143527)
- Adefovir Impurity 8 (CAS 1416439-02-5)
- Isavuconazole Impurity 80 (CAS CATO-C4X-123680)
- 2-Phenyl-1,2,3,4-tetrahydronaphthalene, 97% (CAS 29422-13-7)
- 2-(4-(Phenylthio)phenyl)aceticacid (CAS 6317-61-9)
- N-(2-(4-(Dimethylamino)phenyl)-2-morpholinoethyl)cyclopentanecarboxamide (CAS 1005305-24-7)
- 4-(3-Chloro-1-benzothiophen-2-yl)-2,6-dimethylpyridine-3,5-dicarbonitrile (CAS 477886-64-9)
- 4,4'-Bis(4-methyl-1H-imidazol-1-yl)-1,1'-biphenyl (CAS 1789726-52-8)
- Atracurium Impurity 21 (CAS CATO-C4X-185021)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com