3,3-Difluoro-1-(2-fluoro-6-(trifluoromethyl)-phenyl)azetidine 1707367-49-4 CAS 1707367-49-4
| CAS No. | 1707367-49-4 |
| Molecular Formula | C10H7F6N |
| Molecular Weight | 255.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3,3-Difluoro-1-(2-fluoro-6-(trifluoromethyl)-phenyl)azetidine 1707367-49-4 (CAS 1707367-49-4), molecular formula C10H7F6N and molecular weight 255.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3,3-Difluoro-1-(2-fluoro-6-(trifluoromethyl)-phenyl)azetidine 1707367-49-4 (C10H7F6N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3,3-Difluoro-1-(2-fluoro-6-(trifluoromethyl)-phenyl)azetidine 1707367-49-4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F6N |
| Molecular Weight | 255.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)azetidine (CAS 1713160-22-5)
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- 6,7-Difluoro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 1269531-43-2)
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Recommended Standards
- 2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1420998-43-1)
- [2-amino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol (CAS 1339927-45-5)
- 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)morpholine (CAS 1315281-09-4)
- ((2-Bromothiazol-4-yl)imino)dimethyl-l6-sulfanone (CAS 2920965-37-1)
- 2-(N-benzylmethylsulfonamido)benzoic acid (CAS 333357-38-3)
- 4-Nitrophenylsulfur Pentafluoride (CAS 2613-27-6)
- Ethyl 2-[[cyano-(3,4-dichlorophenyl)-methyl]amino]acetate hydrochloride (CAS 1440535-44-3)
- Betamethasone Impurity 126 (CAS 90039-84-2)
- 1-[3-(4-Chlorophenyl)-1H-pyrazol-4-yl]-1H-1,2,4-triazole (CAS 303996-63-6)
- 4-Methylcinnolin-8-amine (CAS 872284-87-2)
- 7-bromo-5-nitro-2,3-dihydrobenzo[b][1,4]dioxine (CAS 69464-52-4)
- 3-(m-Tolyl)-1,3,4-oxadiazol-2(3H)-one (CAS 139127-30-3)
- 5-Fluoro-1-naphthaldehyde (CAS 110931-86-7)
- Polymyxin B nonapeptide (CAS 86408-36-8)
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