3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)azetidine CAS 1713160-22-5
| CAS No. | 1713160-22-5 |
| Molecular Formula | C10H7F6N |
| Molecular Weight | 255.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.16 g/mol gives 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)azetidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)azetidine (CAS 1713160-22-5) is a high-purity analytical reference standard with the molecular formula C10H7F6N and a molecular weight of 255.16 g/mol.
The molecular framework of 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)azetidine (C10H7F6N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3,3-Difluoro-1-(3-fluoro-2-(trifluoromethyl)-phenyl)azetidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F6N |
| Molecular Weight | 255.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 3,3-Difluoro-1-(2-fluoro-6-(trifluoromethyl)-phenyl)azetidine 1707367-49-4 (CAS 1707367-49-4)
- 3,3-Difluoro-1-(4-fluoro-2-(trifluoromethyl)-phenyl)azetidine 1779122-29-0 (CAS 1779122-29-0)
- 2-(4,4-difluoro-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)acetic acid (CAS 1461715-18-3)
- 1-(2,4-DIfluoro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester (CAS 1239766-16-5)
- 6,7-Difluoro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 1269531-43-2)
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Recommended Standards
- 2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1420998-43-1)
- ((2-Bromothiazol-4-yl)imino)dimethyl-l6-sulfanone (CAS 2920965-37-1)
- [2-amino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol (CAS 1339927-45-5)
- (S)-2-((Dimethoxyphosphoryl)amino)pentanedioic acid (CAS 211631-99-1)
- N-[(2-fluorophenyl)methyl]cyclohexanamine hydrochloride (CAS 1423025-57-3)
- 5-Bromo-2-(3-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1708401-08-4)
- 5-chloro-1-(propan-2-yl)-1H-1,3-benzodiazole-2-carbaldehyde (CAS 749931-54-2)
- 4-(5-(Hydroxymethyl)-2-oxooxazolidin-3-yl)benzenesulfonamide (CAS 87472-10-4)
- 1-Allyl-6-amino-5,6,7,8-tetrahydroquinolin-2(1H)-one (CAS 1422067-44-4)
- tert-Butyl (3S,4R)-3-amino-4-methylpiperidine-1-carboxylate (CAS 1290191-78-4)
- 4-(Difluoromethyl)-2,5-difluorophenol (CAS 1261839-48-8)
- 5,6-Dichloro-4-hydroxypyrimidine (CAS 88982-91-6)
- (2-(3-(Methoxymethyl)phenyl)cyclopropyl)methanamine (CAS 1488311-79-0)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
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