2′-Deoxy-2′-fluoro-5′-guanylic acid CAS 170784-58-4

Purity 97%+In StockPharmaceutical Standards
CAS No.170784-58-4
Molecular FormulaC10H19FN5O7P
Molecular Weight371.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2′-Deoxy-2′-fluoro-5′-guanylic acid CAS 170784-58-4 chemical structure

Description

2′-Deoxy-2′-fluoro-5′-guanylic acid (CAS 170784-58-4), molecular formula C10H19FN5O7P and molecular weight 371.26 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2′-Deoxy-2′-fluoro-5′-guanylic acid is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 371.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2′-Deoxy-2′-fluoro-5′-guanylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H19FN5O7P
Molecular Weight371.26 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2005
Halogen ContentF-containing
Nitrogen Atoms5

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