3-(Difluoromethoxy)-5-isobutoxythiophene-2-carboxylic acid CAS 1708401-58-4
| CAS No. | 1708401-58-4 |
| Molecular Formula | C10H12F2O4S |
| Molecular Weight | 266.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Difluoromethoxy)-5-isobutoxythiophene-2-carboxylic acid.
3-(Difluoromethoxy)-5-isobutoxythiophene-2-carboxylic acid (CAS 1708401-58-4) is a high-purity analytical reference standard with the molecular formula C10H12F2O4S and a molecular weight of 266.26 g/mol.
The molecular framework of 3-(Difluoromethoxy)-5-isobutoxythiophene-2-carboxylic acid (C10H12F2O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(Difluoromethoxy)-5-isobutoxythiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12F2O4S |
| Molecular Weight | 266.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
- [4-(Difluoromethoxy)phenyl](4-fluorophenyl)methanone (CAS 89076-28-8)
- 2-(Difluoromethoxy)-3-nitro-5-(pyridin-4-yl)pyridine (CAS 1214390-87-0)
- 1-[4-(difluoromethoxy)phenyl]-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 923749-90-0)
- 6-(Difluoromethoxy)-4'-methoxy-[1,1'-biphenyl]-3-amine (CAS 851814-10-3)
- 2-(2-(Difluoromethoxy)-5-hydroxybenzoyl)pyridine (CAS 1261592-28-2)
- 2-(5-(Difluoromethoxy)-2-hydroxybenzoyl)pyridine (CAS 1261677-67-1)
- 2-(2-(Difluoromethoxy)-4-hydroxybenzoyl)pyridine (CAS 1261728-86-2)
- 2-(4-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine (CAS 1261769-48-5)
Recommended Standards
- 1-(4-Methylbenzyl)-4-oxo-1,4-dihydro-[1,2,4]triazolo[5,1-c][1,2,4]triazine-3-carbonitrile (CAS 1707587-06-1)
- cis-3-hydroxy-3-[4-(trifluoromethyl)phenyl]cyclobutane-1-carboxylic acid (CAS 1812175-30-6)
- Trimethylsilyl 2,3,4,5-tetrafluorobenzoate (CAS 1616373-58-0)
- 4-(((2-Amino-7H-purin-6-yl)oxy)methyl)benzonitrile (CAS 1923082-67-0)
- (1S,3R)-3-(2-(4-iodophenyl)-2-oxoethyl)cyclohexane-1-carboxylic acid (CAS 735275-39-5)
- 3-Iodo-2-(trifluoromethylthio)pyridine (CAS 1204234-82-1)
- 2-((Piperidin-2-ylmethyl)thio)-1h-benzo[d]imidazole (CAS 1281942-04-8)
- Chloromethyldimethylphenylsilane (CAS 1833-51-8)
- N-(4-Methylphenyl)-4-nitrobenzenesulfonamide (CAS 109845-76-3)
- 1-[4-(trifluoromethyl)phenyl]pentane-1,3-dione (CAS 258346-70-2)
- N-(2-Chloroethyl) 4-boronobenzamide (CAS 874460-05-6)
- (R)-3-Amino-2-azepanone (CAS 28957-33-7)
- 3-(1-Propyl-1H-1,3-benzodiazol-2-yl)-1,2-dihydropyridin-2-one (CAS 861211-98-5)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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