5-(Ethylsulfonyl)-4-(2-fluorophenyl)thiazol-2-amine CAS 1708445-07-1
| CAS No. | 1708445-07-1 |
| Molecular Formula | C11H11FN2O2S2 |
| Molecular Weight | 286.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Ethylsulfonyl)-4-(2-fluorophenyl)thiazol-2-amine.
CATO supplies 5-(Ethylsulfonyl)-4-(2-fluorophenyl)thiazol-2-amine (CAS 1708445-07-1), a certified reference material (molecular formula C11H11FN2O2S2, MW 286.35 g/mol) for analytical method development and quality control.
5-(Ethylsulfonyl)-4-(2-fluorophenyl)thiazol-2-amine (C11H11FN2O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(Ethylsulfonyl)-4-(2-fluorophenyl)thiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11FN2O2S2 |
| Molecular Weight | 286.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Ethylsulfonyl Standards
- 1-(4-(Ethylsulfonyl)-2-fluorophenyl)-3-methylpiperazine (CAS 1000339-75-2)
- 1-(Ethylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2416488-42-9)
- 1-(ethylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1612173-68-8)
- 3-(Ethylsulfonyl)-4-fluorobenzenesulfonyl chloride (CAS 1354963-44-2)
- 3-(((1-(Ethylsulfonyl)-4,5-dihydro-1H-imidazol-2-yl)thio)methyl)pyridine (CAS 868218-70-6)
- N-(2-(Ethylsulfonyl)ethyl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-carboxamide (CAS 1428366-89-5)
- 2-(4-(Ethylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)acetic acid (CAS 1707602-95-6)
- 6-(Ethylsulfonyl)-2-(2-hydroxyethyl)-2H-1,4-benzoxazin-3(4H)-one (CAS 860648-57-3)
Recommended Standards
- 5-(3-(2,4-Dimethylphenyl)-1,2,4-oxadiazol-5-yl)-4-methylthiazol-2-amine (CAS 1707609-30-0)
- 5-(Isopropylsulfonyl)-2-morpholinopyrimidin-4-amine (CAS 175202-03-6)
- 2-(2-Phenyl-4H-thiochromen-4-ylidene)malononitrile (CAS 15058-08-9)
- Ethyl 2-{[(2Z)-azepan-2-ylidene](cyano)methanesulfonyl}acetate (CAS 1785899-58-2)
- 4-methylpiperazine-2,6-dione (CAS 60725-35-1)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzohydrazide (CAS 1191063-60-1)
- (R)-Tetrahydrofuran-2-carbonyl chloride (CAS 148151-47-7)
- Thiamylal (CAS 77-27-0)
- 2-Bromo-6-hydrazinylbenzonitrile (CAS 1260982-77-1)
- 2-Chloro-3,5-dibromo-4-fluorotoluene (CAS 1160574-79-7)
- 3-Butyl-1-ethyl-1,4,5,6,7,8-hexahydropyrazolo[3,4-b]azepine (CAS 583811-95-4)
- Diisopropyl 1-(4-acetylphenyl)-1H-pyrazole-3,4-dicarboxylate (CAS 853407-27-9)
- 2-methyl-3-(piperidin-2-yl)propanoic acid hydrochloride (CAS 1909336-01-1)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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