2,2-difluoro-2H-1,3-benzodioxole-5-sulfonamide CAS 1710471-90-1

Description

Compared with other compounds in its class, the molecular weight of 237.18 g/mol gives 2,2-difluoro-2H-1,3-benzodioxole-5-sulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2,2-difluoro-2H-1,3-benzodioxole-5-sulfonamide (CAS 1710471-90-1), molecular formula C7H5F2NO4S and molecular weight 237.18 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,2-difluoro-2H-1,3-benzodioxole-5-sulfonamide (C7H5F2NO4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com