Lacosamide EP Impurity F (S-Isomer) CAS 171623-03-3
| CAS No. | 171623-03-3 |
| Molecular Formula | C12H16N2O3 |
| Molecular Weight | 236.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 236.27 g/mol gives Lacosamide EP Impurity F (S-Isomer) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Lacosamide EP Impurity F (S-Isomer) (CAS 171623-03-3), a pharmacopoeial impurity reference standard (molecular formula C12H16N2O3, MW 236.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Lacosamide EP Impurity F (S-Isomer) is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O3 |
| Molecular Weight | 236.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Nitrogen Atoms | 2 |
Related Lacosamide Standards
- Lacosamide EP Impurity F (R-isomer) (CAS 175481-38-6)
- Lacosamide Solution EP Impurity F (CAS 171623-02-2)
- Lacosamide Impurity 54 (CAS CATO-C4X-183054)
- Lacosamide Impurity 57 (CAS 862372-15-4)
- Lacosamide Impurity 45 (CAS CATO-C4X-183045)
- Lacosamide Impurity C59 (CAS 1466-67-7)
- Lacosamide Impurity 50 (CAS 2295925-92-5)
- Lacosamide Impurity 53 (CAS CATO-C4X-183053)
Recommended Standards
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- Eplerenone Impurity 14 (CAS CATO-C4X-163014)
- 1-(4-Ethylphenoxymethyl)-1h-pyrazole-3-carboxylic acid (CAS 1006487-25-7)
- 1-(5-Bromo-3-fluoropyridin-2-yl)propan-1-amine (CAS 1270426-95-3)
- (R)-1-Z-2-tert-butyl-3-methyl-4-imidazolidinone (CAS 119906-46-6)
- n-(2-(2-Chlorophenoxy)ethyl)acetamide (CAS 282104-60-3)
- Sivelestat sodium impurity 45 (CAS CATO-C4X-212345)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
Why CATO?
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