Lacosamide EP Impurity F (R-isomer) CAS 175481-38-6
| CAS No. | 175481-38-6 |
| Molecular Formula | C12H16N2O3 |
| Molecular Weight | 236.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lacosamide EP Impurity F (R-isomer) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Lacosamide EP Impurity F (R-isomer) (CAS 175481-38-6) is a certified pharmaceutical impurity reference standard with the molecular formula C12H16N2O3 and a molecular weight of 236.27 g/mol.
The molecular framework of Lacosamide EP Impurity F (R-isomer) (C12H16N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O3 |
| Molecular Weight | 236.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Related Lacosamide Standards
- Lacosamide EP Impurity F (S-Isomer) (CAS 171623-03-3)
- Lacosamide Solution EP Impurity F (CAS 171623-02-2)
- Lacosamide Impurity 54 (CAS CATO-C4X-183054)
- Lacosamide Impurity 57 (CAS 862372-15-4)
- Lacosamide Impurity 45 (CAS CATO-C4X-183045)
- Lacosamide Impurity C59 (CAS 1466-67-7)
- Lacosamide Impurity 50 (CAS 2295925-92-5)
- Lacosamide Impurity 53 (CAS CATO-C4X-183053)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com