3-Amino-6-chloro-2-pyrazinecarbonitrile CAS 17231-50-4
| CAS No. | 17231-50-4 |
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-6-chloro-2-pyrazinecarbonitrile (C5H3ClN4) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Amino-6-chloro-2-pyrazinecarbonitrile (CAS 17231-50-4) is a high-purity analytical reference standard with the molecular formula C5H3ClN4 and a molecular weight of 154.56 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-6-chloro-2-pyrazinecarbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 4-Amino-5-chloropyrimidine-2-carbonitrile (CAS 1260863-79-3)
- 2-Amino-4-chloropyrimidine-5-carbonitrile (CAS 1393179-35-5)
- 2-Amino-6-chloropyrimidine-4-carbonitrile (CAS 2091438-66-1)
- 3-Amino-5-chloropyrazine-2-carbonitrile (CAS 54632-11-0)
- 3-Amino-6-chloropyridazine-4-carbonitrile (CAS 64613-52-1)
- 4-Amino-2-chloro-5-pyrimidinecarbonitrile (CAS 94741-69-2)
- 5-Amino-6-chloropyridazine-4-carbonitrile (CAS 212138-89-1)
- 6-Amino-2-chloropyrimidine-4-carbonitrile (CAS 64376-18-7)
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- tert-Butyl L-N-(3-Benzyloxycarbonylamino-3-(S)-tert-butylcarboxy-1-oxopropyl-azetidine-2-carboxylate (CAS 201283-53-6)
- 3-Amino-6-bromo-2-((4-bromophenyl)amino)quinazolin-4(3H)-one (CAS 91539-11-6)
- 6-Indolecarbonitrile (CAS 15861-36-6)
- Darolutamide Impurity 27 (CAS 1297538-27-2)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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