Moxifloxacin Impurity 28 CAS 172426-88-9
| CAS No. | 172426-88-9 |
| Molecular Formula | C14H13FN2O4 |
| Molecular Weight | 292.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 292.26 g/mol gives Moxifloxacin Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Moxifloxacin Impurity 28 (CAS 172426-88-9, C14H13FN2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Moxifloxacin Impurity 28 (C14H13FN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13FN2O4 |
| Molecular Weight | 292.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Moxifloxacin Standards
- Moxifloxacin Impurity 153 (CAS 1048972-52-6)
- Moxifloxacin Impurity 109 (CAS 1641561-55-8)
- Moxifloxacin Impurity 12 (CAS 112811-72-0)
- Moxifloxacin impurity 175 (CAS 104599-90-8)
- Moxifloxacin Impurity 27 (CAS 94695-52-0)
- Moxifloxacin Impurity 71 (CAS 56113-42-9)
- Moxifloxacin Impurity 23 (CAS 154093-72-8)
- Moxifloxacin Impurity 170 (CAS CATO-C4X-1074170)
Recommended Standards
- tert-Butyl 2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazine-7(8H)-carboxylate (CAS 681249-59-2)
- Sitagliptin Impurity 64 (CAS 877402-43-2)
- N-Methyl-3-(4-(trifluoromethyl)phenyl)imidazo[1,2-a]pyrazin-8-amine (CAS 787590-94-7)
- N1-(4-Fluorobenzyl)-N2-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)oxalamide (CAS 1209246-72-9)
- Lornoxicam impurity 64 (CAS CATO-C4X-201664)
- Deruxtecan Impurity 3 (CAS CATO-C4X-30573)
- Rivaroxaban impurity 29 (CAS CATO-C4X-109029)
- Ethyl 3-[4-(benzyloxy)phenyl]-3-oxopropanoate (CAS 53090-45-2)
- 5-Bromo-2-(piperidin-3-yloxy)pyridine (CAS 1250803-96-3)
- N1-(6-methylpyridin-2-yl)ethane-1,2-diamine dihydrochloride (CAS 1311316-96-7)
- 2-[(2,6-Dichlorobenzyl)oxy]-3-methoxy-benzoyl chloride (CAS 1160251-01-3)
- 5,7-Dichlorobenzo[d]thiazol-2-amine (CAS 158465-13-5)
- 32638-88-3 Pyrogallol sulfonphthalein Benzenesulfonic acid, 2-(4,5,6-trihydroxy-3-oxo-3H-xanthen-9-yl)- Spiro(3H-2,1-benzoxathiole-3,9'-(9H)xanthene)-3',4',5',6'-tetrol, 1,1-dioxide AI3-63037 EINECS 251-134-3 (CAS 32638-88-3)
- Characteristic MSH-Tetrapeptide (CAS 4289-02-5)
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