2-Hydroxy-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one CAS 17326-10-2

Purity 97%+In StockPharmaceutical Standards
CAS No.17326-10-2
Molecular FormulaC9H8N2O2
Molecular Weight176.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Hydroxy-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one CAS 17326-10-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 176.17 g/mol gives 2-Hydroxy-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Hydroxy-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 17326-10-2), molecular formula C9H8N2O2 and molecular weight 176.17 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-Hydroxy-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (C9H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 176.17 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Hydroxy-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H8N2O2
Molecular Weight176.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms2

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